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As expected, the primary adverse events were related to the gastrointestinal system, with nausea and vomiting being the most common
however, clinically viable GLP-1 receptor agonists did not emerge until advances in peptide stabilization, delivery, and dosing strategies were achieved ( The delayed translation of GLP-1 illustrates a critical principle: biological validity alone is insufficient for therapeutic success
The proportion of patients with rectal bleeding increased over the first 12 years after radiotherapy and decreased thereafter (Fig
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