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If your migraines get worse, it can be hard to tell whether thats the Mounjaro or a coincidence

C., Senyucel, C., & Dunn, J

Additionally, the rate of intestinal transit affects how much bile pigment (which gives stool its brown colour) is broken downfaster transit may result in greener stools, whilst slower transit typically produces darker brown stools

Pharmacodynamic Effects and Duration Despite measurable plasma clearance, pharmacodynamic effects extend well beyond plasma half-life[20]: Weight loss effects continue throughout treatment with no plateau observed within 48-week study periods Glycemic improvements persist between weekly doses with stable glucose control Appetite suppression effects remain consistent throughout dosing intervals Tissue receptor occupancy likely exceeds plasma peptide concentrations This disconnect between pharmacokinetics and pharmacodynamics suggests prolonged receptor engagement, tissue depot effects, or persistent downstream signaling cascade activation