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Direct effects on isolated pancreatic cells Study of possible direct effects of GLP-1 on acini began with the discovery of biologically active peptides in Gila monstor venom (33, 34) and the identification of a specific receptor for Exendin-4 on guinea pig isolated pancreatic acini that increased the production of cAMP (93, 94)
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A., Gething, P
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The critical objective for the next phase of research is not to redundantly prove weight loss efficacy, but to determine whether and through which pathways these gains translate into benefits for hard reproductive endpoints
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Around the same time, the Food and Drug Administration (FDA) in the United States and the Medicines and Healthcare Product Regulatory Agency (MHRA) in the United Kingdom undertook similar evaluations
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