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Gastroenterology 2008
Oral B12 supplementation may be appropriate in specific circumstances: Dietary deficiency in individuals with normal absorption capacity (typically 50-150 micrograms daily) Patient preference (after discussion of relative efficacy) Maintenance therapy in selected cases Higher oral doses (10002000 micrograms daily) may be used in some cases, as only a small percentage is absorbed through passive diffusion when intrinsic factor-mediated absorption is impaired
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The phase transfer of GSH-AuNCs by DDA to the organic solvents can be achieved equally by two methods: 1) addition of DDA in methanol to GSH-AuNCs in water to form a milky suspension followed by addition of the water-immiscible organic solvent to extract the DDA-GSH-AuNCs or 2) starting with a biphasic system of GSH-AuNCs in water and a water-immiscible organic solvent containing DDA followed by addition of methanol
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