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Unintentional weight loss, more likely driven by comorbid disease, excessively impacts metabolically active tissue over fat mass [45]
2023;146:104471.[DOI] 174
Everyone starts at the lowest dose to help reduce side effects, like nausea, and give the body time to adjust
GLP-1 agonists have evidence supporting longer-term use and act on metabolic signaling directly, which is why the article treats duration as a core difference rather than a technicality
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