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For instance, while many of the GLP-1 drug interactions investigated to date may be statistically significant , no dose adjustment is required because they were not found to be clinically relevant . The one exception is tirzepatide, as described above

PEG-MGF PEG-MGF is a pegylated analog of Mechano Growth Factor, a splice variant of IGF-1 studied for its role in muscle repair and satellite cell activation

This approach could enable initial treatment with highly effective but expensive GLP-1 agonists, followed by maintenance with more affordable alternatives

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