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Inflammation increases leptin concentrations and lowers adiponectin, presenting a favorable environment that could enhance cancer proliferation in the tumor microenvironment
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Researchers use it as a tool compound in cell-based receptor assays, adipocyte and hepatocyte studies, and rodent models of obesity, type 2 diabetes, and metabolic disease
The combination of GLP-1 and GIP receptor activation in the central nervous system may achieve more balanced and sustained effects on energy homeostasis compared to targeting either pathway alone
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