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It includes positron emission tomography-magnetic resonance (PET MRI) studies of plaque inflammation (plaque 18 F-FDG and 68 Ga-DOTATATE uptake), MRI for plaque morphology and burden, as well as biomarkers, proteomics and RNA profiling, myocardial perfusion reserve and changes in carotid artery total wall volume

Patients should be counseled that weight loss plateaus are normal and do not indicate medication failure

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