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This increased acidity might induce formation of peroxynitric acid or peroxynitrites, which are important species for decontamination processes 66
Moreover, lipid nanocapsules (LNCs) loaded with load-laurylated gemcitabine (GemC12) can effectively target the monocytic (M-) MDSC subset, and subcutaneous injection of GemC12-loaded LNCs can enhance tumor immunotherapy by reducing the proportion of M-MDSCs in splenic and tumor-infiltrating monocytes, with efficacy higher than that of free gemcitabine (120)
With chronic overexposure, they cause tissue degradation
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