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It participates in the regulation of immune response, ensures effective pathogen neutralization, and helps recover from infections
The exception may be efgartigimod, as the pH-dependency of its binding to FcRn entails that it may be released at the fetal side of the placenta upon exposure to physiological pH
The concentration of IL-1 and IL8 were measured quantitatively using ELISA kits in accordance with the manufacturers instructions
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