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speculated that there did not seem to be any known pathway that would generate a purple metabolite, and that the urine coloration was likely the result of the combination of the blue and red colors from methylene blue and hydroxocobalamin, respectively [15]
These are particularly useful for individuals who are only mild to moderately deficient
[40] Endogenous vitamin B 12 becomes inactive when exposed to hydrogen cyanide and nitric oxide in cigarette smoke
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