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Common signs include: Fatigue Weakness Anemia Pale or yellowish skin Numbness or tingling in the hands and feet Difficulty with balance Glossitis (a swollen, red tongue) Memory or concentration difficulties If you suspect you may have a vitamin B12 deficiency, consult your healthcare provider for appropriate testing and personalized recommendations
Zhou, Y., Wang, S., Li, Y., Yu, S
Up to now, powerful genetic tools allowed clarification of the significance, dispensability and potential of cystine transporters for ferroptotic cell death in PDAC and breast cancer ( via xCT ( A high extracellular glutamate concentration was one of the first xCT inhibitors described but a few years later, erastin (standing for eradicator of RAS and small T antigen-expressing cells) was identified by Stockwell's group in RAS-mutated cancer cell lines as inhibitor of xCT transport ( in vitro studies as efficient inducer of ferroptosis in many different cancer types, including breast, PDAC, lymphoma, renal, brain and ovarian cancers ( via transsulfuration pathway is a potential resistance mechanism under cysteine depletion conditions
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