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These are not my words these are the words of a rheumatologist Dear Bellabab, Im sorry you feel we are making pointless comments
Moreover, mitochondrial dysfunction and related oxidative stress can activate the innate branch of the immune system, leading to the release of pro-inflammatory cytokines influencing various depression-related pathophysiological mechanisms: monoaminergic neurotransmission disruption, tryptophan degradation toward neurotoxic catabolites, glutamate-related excitotoxicity, decreased neurotrophic factors and alterations in the hypothalamic-pituitary-adrenal axis [3, 33, 59]
GI Problems: Sometimes oral supplements cause diarrhea, bloat, or upset of the stomach
Kapadia R, Yi JH, Vemuganti R
