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While Merrill sees potential for the future of GLP-1 drugs to be helpful outside treating type 2 diabetes and obesity, he also understands the need for more studies

However, GLP-1 RAs significantly increased the change in the 6-min walk test (MWT) distance (MD: 19.74, p = 0.002)

This means that while its proposed mechanisms are interesting and its reported side effect profile in available research and anecdotal use tends to be relatively mild, theres still considerable uncertainty about long-term effects and optimal dosing in humans

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