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One of the main causes of insomnia is menopause, which is accompanied by hot flashes and nocturnal sweats
It has also been identified as a contributing factor to variations among individuals through its unique, individual-specific signatures [290]
The efficacy of this therapeutic combination was first validated in our breast cancer models, demonstrating that PHGDH wild type breast cancer cells do not respond to the therapeutic combination, whereas PHGDH-amplified breast cancer cells exhibited a synergistic sensitivity to suboptimal dosages of sertraline plus chloroquine (Figure S8A)
The natural decline of GHK-Cu can be as much as 60% by age 60
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