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The cells were subsequently tested by flow cytometry

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After stimulation with phototherapy, these melanoblasts migrate, differentiate into melanocytes, and proliferate into the epidermis, probably through the upregulation of the stem cell-associated gene, GLI1.40 The stratum corneum and viable epidermis of vitiligo lesions are increased in thickness compared to non-lesional skin.41 The lesional epithelium also has larger corneocytes, likely to compensate for the decreased expression of cornification components and, therefore, they result in a thicker stratum corneum in vitiligo lesions

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2011, PMID 20880960

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