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EMERGING RESEARCH: WHAT THE SCIENCE SAYS While we are still awaiting large-scale clinical trials specifically for lipedema, recent pilot studies and reviews are promising: The "Italian Pilot Study" (Exenatide): A recent pilot study looked at women with lipedema and insulin resistance treated with a GLP-1 agonist (exenatide)

That's where GLP-1 supplements come in marketed as a more natural, noninjectable way to tap into similar benefits