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During learning phases rats were presented with two identical objects (one pair/phase)

Clinical studies most often report mild side effects, including nausea, vomiting, diarrhea, heartburn, gas, headache, and general digestive discomfort.27 A 2021 safety review of high-dose NAC in chronic respiratory diseases found that oral doses between 600mg and 3,000mg daily were generally well tolerated, with gastrointestinal symptoms reported but not consistently more often than placebo.35 That doesnt mean NAC is risk-free

Methods All the data mentioned below was obtained from both groups at the initiation of KD and after 3 months of intervention and all enrolled patients completed the follow up assessment

The first: if your PCOS presentation is inflammation-driven you have an autoimmune overlay, your inflammatory markers run high, you suspect gut permeability is part of what is going on NAC's antioxidant and anti-inflammatory mechanism is more directly relevant to your specific picture, and a NAC adjunct on top of the better-evidenced foundation is defensible