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Exerts cytoprotective effects by blocking pro-apoptotic Bax protein, reduces oxidative stress, and supports cellular energy production
REDEFINE-4 reported about 25.5% at 84 weeks in a head-to-head trial
When there are reduced levels of PTH in the circulation the CYP24A1 gene is active leading to the stimulated synthesis of the inactive 24,25-(OH) 2 D 3
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