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Results Peripheral administration of GLP-1R analogues does not affect CSF dynamics in rats To determine whether the reported GLP-1-mediated modulation of ICP [21] originated in altered CSF secretion, we employed the synthetic agonist exendin-4 (Ex4) which has longer systemic half-live than GLP-1, due to insensitivity to the protease dipeptidyl peptidase 4 [34, 35] and the synthetic antagonist exendin-9-39 (Ex9-39)

I'm 60+ & have had UC since my early 20's

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