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Proc Nutr Soc 74(4):355366 Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I et al (2021) Once-Weekly semaglutide in adults with overweight or obesity
GLP-1 medications can help by reducing appetite and cravings, making it easier to maintain the calorie deficit needed for fat loss
The degree of appetite reduction varies considerably between individuals
We examine the profound dysregulation of the gelatinases and collagenases MMP-2, 8, and 9, exploring how their hyper-activation transitions from localized tissue destructionsuch as hair follicle rupture and sinus tract formationto systemic inflammatory and metabolic complications
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