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The comparator groups differed among studies, with some employing placebo controls (e.g., PIONEER-6, Gerstein 2019), others using active comparators such as sitagliptin, glimepiride, DPP-4 inhibitors, or SGLT2 inhibitors, and some utilizing standard care or intensive lifestyle interventions as the control

Benefits may include a brighter complexion, improved skin clarity, reduced appearance of dark spots, enhanced detoxification, stronger immune support, and antioxidant protection against cellular aging