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It also serves to regulate activities of vital organs and blood vessels, as well as communication between nerves and muscles

Third, although direct anti-inflammatory effects of tirzepatide have not been as extensively documented as those observed with GLP-1 agonists alone, its dual incretin receptor activation is widely hypothesized to modulate generation of reactive oxygen species pro-inflammatory cytokine production [21]

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The above evidence suggests that crosstalk between microglia and Tregs is a key determinant of neuronal regeneration and the repair of synaptic plasticity after brain injury (97)