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Veterinary dermatology , 19 (1), 714
The ranking of therapies is based on their pathway-targeting effectiveness within the DM2-AD comorbidity network, and while metformin demonstrates the highest engagement with key neuroprotective mechanisms, and semaglutide among the least, this does not imply complete inefficacy of lower-ranked therapies
The broader class of GLP-1 RAs has generated an increasingly positive body of evidence, providing additional context for understanding tirzepatide specifically
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