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The Warburg effect (aerobic glycolysis) observed by Otto Warburg nearly a century ago is the phenomenon that cancer cells preferentially convert most glucose to lactate even in the presence of oxygen by which mitochondrial oxidative phosphorylation can proceed to generate ATP more efficiently(9, 10)
Controls Angiogenesis: vascular density +200% (IGF-1-mediated) Collagen deposition: increased matrix synthesis Re-epithelialization: keratinocyte migration +150% 3
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