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Senolytic therapies may be an effective approach for preventing cancer recurrence and therapy resistance
For T0901317 experiments, mice were injected intraperitoneally with either vehicle (10%DMSO in 90% corn oil) or T0901317 (MedChem Express, HY-10626) at a dose of either 16.9 mg/kg or 50 mg/kg dose for either 4 days (1720) days post AAV-TBG-Cre treatment) or 14 days (720) days post AAV-TBG-Cre treatment)
Checkpoints: controls that ensure the order of cell cycle events
What they discovered over decades of research is that its effects extend well beyond the gut
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