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This is a long-term, sustainable protocol with ongoing clinician monitoring for optimization
GLP-1RAs directly stimulate POMC/CART neurons and indirectly inhibit NPY and AgRP to increase measures of satiety and decrease hunger, resulting in reduced energy intake, thereby facilitating weight loss (Ard et al., 2021) (Figure 6)
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Although RA-specific GLP-1 nanotherapeutics remain under development, albumin NPs have shown efficacy as carriers
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