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Surgery for bilateral endometrioma is associated with a lower age at onset of menopause 54 and a small risk (2.4%) of immediate post-surgical premature ovarian insufficiency
Taken together with precedent from oncology, the overall evidence indicates that Erastin has clear therapeutic potential for EMS, provided drug delivery preferentially targets lesions while sparing healthy tissue
In UK practice, monitoring is primarily based on clinical response rather than routine blood tests, as post-treatment serum B12 measurements can be misleadingly high and may not reflect tissue levels
& McClure, R
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