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As patients lose weight on GLP-1 therapy, increased mobility often becomes feasible, creating opportunities for enhanced physical activity that further supports weight management and joint function

Kapil S, Duseja A, Sharma BK, Singla B, Chakraborti A, Das A, et al

"This is the first clinical trial to demonstrate that semaglutide may improve liver fibrosis in patients with advanced MASH, including those with compensated cirrhosis," said Rohit Loomba, MD, senior author of the study, gastroenterologist and hepatologist at UC San Diego Health and chief of the Division of Gastroenterology and Hepatology at UC San Diego School of Medicine

The 2026 Regulatory Landscape The legal foundation for compounded GLP-1 medications shifted in early 2026