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Lessons from the Failure to Complete a Trial of Denosumab in Women With a Pathogenic BRCA1/2 Variant Scheduling Risk-Reducing Salpingo-Oophorectomy
Hudgins L, Hopwood VL, Hu PC , Glassman A
The parent compound is proposed to interact with gene regulatory regions, including the hTERT (telomerase reverse transcriptase) promoter, modulating telomerase expression in somatic cells
Side effects during the first week at 1 mg can be challenging for some people
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