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Other downregulated processes included those involved in the pathogenesis of a variety of cardiomyopathic states, including cardiac muscle contraction, hypertrophic cardiomyopathy, dilated cardiomyopathy, and diabetic cardiomyopathy

Wadden and colleagues assessed changes in depressive symptoms using the Patient Health Questionnaire-9 (PHQ-9) and suicidal ideation or behaviors using the Columbia Suicide Severity Rating Scale in participants with overweight or obesity using semaglutide 2.4 mg or placebo