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Further, it was explained that the appetite-reducing effects promoted by GLP-1R stimulation effectively reduce caloric intake by inducing satiety and delaying gastric emptying, making it a prime target to counter hyperglycemia and overeating [107]

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Practical comfort strategies include allowing injector pens to reach room temperature before use (never inject cold medication directly from refrigeration), pinching the skin gently to create a firmer injection surface, and injecting slowly to let tissue gradually accommodate the needle

Foods to limit or avoid include high-fiber items like raw vegetables and whole grains, fatty or fried foods that slow digestion further, and carbonated beverages that increase bloating