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Mood and Mental Health Impact Given that semaglutide does not directly target mental health, some researchers are curious about whether it might still affect mood and mental states when taken with SSRIs

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Occasional cortisol spikes might not contribute to rapid weight gain, but studies have found links between long-term cortisol increases and obesity

Research suggests the medication may enhance satiety signals and potentially affect food reward mechanisms, making it easier for many individuals to adhere to reduced-calorie diets