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Available reports describe 5-Amino-1MQ as selective for NNMT within tested experimental panels, but those panels do not equal a complete off-target safety profile across all methyltransferases, non-methyltransferase proteins, cell types, exposure durations, or intracellular conditions

Incorporating antioxidants, either through diet or skincare, can help counteract some of the damage caused by these habits, allowing the skin to maintain an even tone

Shuo Hu, [email protected] These authors have contributed equally to this work This article was submitted to Biomaterials, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

While results may develop more gradually than with some aggressive treatments, the improvements tend to be more sustainable and come without the risk of long-term damage or irritation that can accompany harsher approaches