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GLP-1 analogues, including semaglutide and tirzepatide, have shown favorable safety profiles in clinical trials
The Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence 17 was used to grade the quality of evidence (OCEBM)
Treatment of pre-existing obesity: animals with genetic mutations (ob/ob or db/db mice) causing obesity or high-fat diet-induced obesity at baseline
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