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It binds to and activates MC4R receptors concentrated in the hypothalamus the brain region that regulates sexual behavior, appetite, and autonomic function
Symptoms of PAD can include a persistent cold sensation, leg pain with walking (claudication), slowed healing of cuts, and changes in skin color or hair growth
Oh B, Lee KJ, Zaslawski C, Yeung A, Rosenthal D, Larkey L, Back M
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