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This size is suitable for injecting into the fatty tissue just below the skin
GHK-Cu displaces Keap1s Cu coordination (Log K ~16 for GHK-Cu versus ~8 for Keap1 cysteine-zinc coordination) to stabilise Nrf2 and drive nuclear translocation
Notably, potential toxicity of accumulated metals can be decreased as a result of the formation and subsequent sequestration of metal-PC complexes in vacuoles via transport across the tonoplast (Cobbett and Goldsbrough, Caenorhabditis elegans PCS gene that control PCs production
Agarwal A, Said TM, Bedaiwy MA, Banerjee J, Alvarez JG
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