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3.1 GLP-1 receptors in the brain GLP-1 receptors are expressed in various regions of the brain, in addition to the pancreas and gut, highlighting the hormones function as a neuropeptide in the brain

Tirzepatide, a newer and more potent GLP-1 receptor agonist than semaglutide, also targets glucose-dependent insulinotropic polypeptide (GIP) to enhance GLP-1s effects in regulating blood sugar

This additional step was imperative for conducting direct evaluation of the hypothesis that LASSS interacts/reacts with HGF to augment its c-met binding affinity