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Vitamin C helps regenerate other antioxidants, especially glutathione, which makes it one of the more accessible, natural ways to boost glutathione levels through diet and supplementation

The primary role of GSTs is to detoxify xenobiotics by catalyzing the nucleophilic attack by GSH on electrophilic carbon, sulfur, or nitrogen atoms of said nonpolar xenobiotic substrates, thereby preventing their interaction with crucial cellular proteins and nucleic acids

Antioxid Redox Signal 38(13):10011021 Nguyen T, Jeyakumar A (2019) Genetic susceptibility to aminoglycoside ototoxicity