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Studies on athletes show whole-body cryotherapy reduces circulating levels of the pro-inflammatory cytokine IL-1 beta while increasing the anti-inflammatory cytokine IL-10 and the cytokine inhibitor IL-1 receptor antagonist (IL-1ra)
Stein, K
Preclinical studies have observed its modulatory effects on corticotropin and somatostatin secretion, suggesting its role in neuropeptide feedback loops relevant to stress adaptation and hormonal rhythms
J Chin Med Assoc 88:495502
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