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Not long ago, managing appetite was mostly about willpower, strict dieting, or simply eating less. Today, the conversation is shifting toward the hormones that actually drive hunger and energy balance especially GLP-1
It is reported that LC increases GnRH secretion from the hypothalamus by acting on the HPG axis [16, 17] and causing K + -induced depolarization in hypothalamic neuronal cells to increase its secretory activity [80, 81]
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