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These findings strengthen our conclusion that the bioenergetic improvements induced by low-dose 2DG are attributable to both an increased number of mitochondria and enhanced efficiency of individual mitochondria, highlighting its potential as a metabolic modulator in the CNS
As of mid-2026, neither cagrilintide nor retatrutide is FDA- or EMA-approved for any indication, and no legitimate prescription product exists for either
Although the neuroprotective credentials of statins in PD are mainly attributed to regulating inflammatory pathways, prolonged statin therapy and the associated lipid lowering effect can backfire on neurons in PD
95% CI, 1.59-4.08)
