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In addition, citrulline, a major precursor for endogenous arginine, supplementation has been shown to restore systemic arginine levels, improve airway NO production, and asthma control in individuals with obesity-related asthma [124]
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It is susceptible to carboxypeptidase cleavage, light-driven copper photo-oxidation and pH extremes, with an optimum of about 5.0 to 6.5
This indicates that low GSH can indirectly reduce permeability via increased efflux
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