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Maher P, Dargusch R, Bodai L, Gerard PE, Purcell JM, Marsh JL (2011) ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntingtons disease
USA 110 , E1152E1161 (2013)
In most chronic cases, no specific trigger can be identified
The positive outcome may be attributed to the profound impact of ketones on multiple targets, including but not limited to glutamate/GABA transmission, monoamine levels, mitochondrial function and biogenesis, neurotrophism, oxidative stress, insulin dysfunction, and inflammation, and demonstrates mood-stabilizing and antidepressant effects (100)
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