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Here, we demonstrated that long-term oscillating glucose challenge in vivo resulted in desensitization of insulin secretion due to -cell mass exhaustion, which was caused by -cell dedifferentiation
Study #1 The first study was performed in 1991, on 20 women with no periods
The third term is the loss of cysteine in the reaction catalyzed by GCS that makes glutamyl-cysteine and the fourth term represents the loss of cysteine to other pathways (for example to sulfate and taurine)
AB: Conceptualization, Data curation, Writing original draft, Writing review & editing, Methodology, Software
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