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What about the frequency
Markers of microbial dysbiosis, such as shifts in the Firmicutes/Bacteroidetes ratio, reduction in butyrate-producing species, and increased LPS levels, may serve as early indicators of circadian-gut axis dysfunction 260
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Similarly, an intravenous GSH trial found no significant differences in motor or activities of daily living (ADL) scores between the GSH and placebo groups at week 4 or during follow-up, suggesting only minimal symptomatic benefits (Hauser et al., 2009)
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