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Mice were intraperitoneally injected with 3% thiolglycollate medium, and mouse peritoneal macrophages (MPMs) were collected after 72 h
Therefore, purity and amounts of active ingredient can vary significantly between products from different manufacturers
Due to the wide spread of HK-1 in the body, and its preferential affinity to the NK-1 tachykinin receptor, it has been implicated in many diseases (reviewed elsewhere, [103,104,105]) including asthma and possibly COPD [106,107,108]
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