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Administration of a modified mediterranean KD reduces the abundance of harmful bacteria, such as Bifidobacterium and Lachnobacterium , while increasing beneficial microbes, including Enterobacteriaceae , Akkermansia , Slackia , Christensenellaceae , and Erysipelotrichiaceae

Currently, a major gap in the field that applies here relates to the need for a diagnostic biomarker in humans that correlates with pre-neoplastic disease progression (e.g., indicating a high grade PanIN)

In both animal 8 and human studies 9 a significant improvement in mood was observed following ALCAR supplementation

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