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It belongs to a class of drugs known as multi-receptor agonists, and its mechanism of action is notably broad: it simultaneously activates three hormone receptors the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor
There is no evidence that split dosing produces better outcomes when the once-weekly protocol is already effective
In contrast, SGLT2 inhibitors have shown renal protective effects and may be prioritized in this group
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