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Tirzepatide works by targeting the dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist, making it the first weight loss and diabetes care medication that targets 2 receptor agonists
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In these cases, switching to semaglutide may trigger renewed metabolic response because it activates a different primary pathway and can sometimes restart fat loss momentum
European Journal of Internal Medicine, 24(8), 714-720
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